top of page

Vertical 10.5 mm TSE 40:1 (L/D)

background8_edited_edited.jpg

Our patented vertical set-up improves material flow, facilitates smoother mixing, provides superior temperature management and preserves the integrity of sensitive components with varying melt degradation properties.

Please reach out to us via the contact form below if you require a configuration that is not listed. We make machines to order and can often accommodate specific requests.

For convenience we provide separate specification sheets for machines used for pharmaceutical purposes from battery production or R&D. 


View or download Pharma or R&D/Battery in PDF format.

Compact and efficient design

Maximize productivity and space utilization with our innovative vertical orientation which reduces the extruder footprint (0.5 m²) and allows for low capital intensity.


Durable material contact parts

Experience minimal abrasion extended machine life span with our optimized components.


Easy-to-clean system

Fully disassemblable contact parts (liners, screws elements, dies and plugs) ensure thorough cleaning between batches, full traceability and GMP cross-contamination compliance.


Smooth mixing of fragile active ingredients 

(e.g. APIs, enzymes, peptides and proteins) gentle handling of shear- and heat-sensitive actives.


Versatile screw design and die options

Cater to diverse R&D and production applications with our flexible design features.


Precise monitoring of process temperature

with autonomous control for each of the 8 zones up to 300 °C (450 °C optional).


Integrated controls for feeders

The system supports precise and reliable feeding of powders, pellets, gases, liquids, and supercritical fluids. Feeders can be installed on both sides of the barrel. This high level of integration also allows full modular use of the extruder length, making it possible to operate the same machine effectively in 40:1, 20:1, or intermediate L/D configurations.


Modular downstream platform

Pelletizing, spheronization, calendaring, winding, implant and chewable cutting devices, film slitting and gummy production, adaptable to each application.


Scalability of our continuous manufacturing process

Seamlessly transition from lab testing to industrial production with our scalable geometric proportions.

Dosage forms

  • Solid oral dosage forms (tablets, hard and soft capsules)

  • Orodispersible drugs and nutraceuticals (film granules, tablets, ODTs)

  • Semi-solids (ointments, creams, pastes, gels, suppositories)

  • Controlled-release systems (implants, transdermal films, mucoadhesive films, matrices, pellets, ophthalmic and vaginal devices)

  • Chewable dosage forms and gummies

  • Extrudates for injection molding, calendaring or 3D printing

  • Co-extrusion: multilayer components


Medical devices

  • Medical polymer systems (strips, straps, other medical devices)

  • Medical tubes


Formulation technologies

  • Amorphous solid dispersions or co-amorphous systems

  • Cyclodextrin complexes

  • Solid lipid nanoparticles

  • Taste masking

  • API stabilization

  • Dry and wet granulations


Active ingredient synthesis & extraction

  • Co-crystals

  • Reactive extrusion: continuous polymer synthesis and modification

  • In-situ API synthesis in polymer matrices: one-step synthesis and formulation

  • Continuous botanical active extraction: extraction of actives from plant matrices

Get in touch

Please feel free to ask further questions, request a quote, enquire about customisation, or find out when we will next visit your part of the world.

 

All entries go directly to a member of our team.

Reason for contacting us today
bottom of page